11 Temmuz 2012 Çarşamba
10 Temmuz 2012 Salı
9 Temmuz 2012 Pazartesi
Toronto Star Article on the Acidity of Certain Foods and the Effect on Teeth
To contact us Click HERE
Saw this article in the Toronto Star Health Zone Section this morning. As always, a swish of water after a meal does wonders.
Source: Apple a Day May Keep the Dentist Close, http://www.healthzone.ca/health/dietfitness/article/1067949--apple-a-day-may-keep-the-dentist-close
Published on Oct 11, 2011. Read on October 12, 2011.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Apple a Day May Keep the Dentist Close, http://www.healthzone.ca/health/dietfitness/article/1067949--apple-a-day-may-keep-the-dentist-close
Published on Oct 11, 2011. Read on October 12, 2011.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Dental Did You Know: The Price of John Lennon's Tooth.
To contact us Click HERE
Apparently, John Lennon's molar was sold for about $31000 at the Omega Auction House on November 4th. It went for double its listed price and was originally given by him to his former housekeeper. It is also reported to be now in the possession of a Canadian dentist (not confirmed and not me :)
Source: Rolling Stone Magazine (Online), November 6th, Read November 7th, http://www.rollingstone.com/music/news/john-lennons-tooth-sells-for-more-than-31-000-at-auction-20111106
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Rolling Stone Magazine (Online), November 6th, Read November 7th, http://www.rollingstone.com/music/news/john-lennons-tooth-sells-for-more-than-31-000-at-auction-20111106
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Revealing more about FIP
To contact us Click HERE
Pedersen NC, Liu H, Scarlett J, et al. Feline infectious peritonitis: Role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats. Virus Research 2012;165:17-28.
Feline infectious peritonitis (FIP) is a complex disease involving a mutant coronavirus. The specific mutation that occurs allowing this normally innocuous virus to cause a fatal disease remains unclear. A particular virus protein, the 3c protein, has been investigated as a possible viral mutational site contributing to disease development. These investigators found that this protein appears to be involved with the ability of the virus to replicate in the intestines. Mutations in the gene for this protein lead to the virus being unable to replicate in the intestinal tract and thus unable to be shed in feces. More than half of the FIP viruses they analyzed had a mutation in the 3c gene. This may explain why FIP outbreaks with cat-to-cat transmission of the mutant virus rarely occurs – it is simply no longer shed in feces once this mutation occurs. While we still don’t know what makes the FIP virus so nasty, we have gained a better understanding of its strange epidemiology. [MK]
See also: Brown MA. Genetic determinants of pathogenesis by feline infectious peritonitis virus. Vet Immunol Immunopathol 2011;143:265-268.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Feline infectious peritonitis (FIP) is a complex disease involving a mutant coronavirus. The specific mutation that occurs allowing this normally innocuous virus to cause a fatal disease remains unclear. A particular virus protein, the 3c protein, has been investigated as a possible viral mutational site contributing to disease development. These investigators found that this protein appears to be involved with the ability of the virus to replicate in the intestines. Mutations in the gene for this protein lead to the virus being unable to replicate in the intestinal tract and thus unable to be shed in feces. More than half of the FIP viruses they analyzed had a mutation in the 3c gene. This may explain why FIP outbreaks with cat-to-cat transmission of the mutant virus rarely occurs – it is simply no longer shed in feces once this mutation occurs. While we still don’t know what makes the FIP virus so nasty, we have gained a better understanding of its strange epidemiology. [MK]
See also: Brown MA. Genetic determinants of pathogenesis by feline infectious peritonitis virus. Vet Immunol Immunopathol 2011;143:265-268.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Let's immune system help
To contact us Click HERE
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido,
Vinod P Balachandran, et al. Nature Medicine17 (2011)
I would like to hilight this paper to our readership, as many of your are involved in the design of clinical trials and selection of potential biomarkers. This report is one of a handful of high impact papers that report the coperative role that inflammatory infiltrate and non cell autonomous effectors play in modulating response to established agents. This study demonstrates an interesting immunological mechanism of Imatininb that contributes to the antitumor effect in a Gastrointestinal Stromal Tumor (GIST) mouse model. Inflammatory infiltrate is a known finding in GIST specimens (including intratumoral CD8+ Tcells, Treg cells and macrophages). Acording to the authors, Imatinib activates CD8+ T cells and induces Treg cells apoptosis within the tumor. Imatinib is therefore able to reduce the expression of 2,3-dioxygenase (Ido) of tumor cells. Ido enzyme is involved in the catayzation of immunosuppressive metabolites from tryptophan and therefore mediates downstream immunological response. Interestingly Imatininb resistant tumors, generally as a result of a second KIT mutation, restore the overexpression of IDO and combination of Imatinib with CTLA-4 blockade (a well established immunotherapeutic strategy) act synergistically. This insight provides some hints on something we have been suspecting for a long time. It is easy to predict consequences for rational design of combination therapies and strategies to overcome resistance in Imatinib resistant tumors.
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido,
Vinod P Balachandran, et al. Nature Medicine17 (2011)
I would like to hilight this paper to our readership, as many of your are involved in the design of clinical trials and selection of potential biomarkers. This report is one of a handful of high impact papers that report the coperative role that inflammatory infiltrate and non cell autonomous effectors play in modulating response to established agents. This study demonstrates an interesting immunological mechanism of Imatininb that contributes to the antitumor effect in a Gastrointestinal Stromal Tumor (GIST) mouse model. Inflammatory infiltrate is a known finding in GIST specimens (including intratumoral CD8+ Tcells, Treg cells and macrophages). Acording to the authors, Imatinib activates CD8+ T cells and induces Treg cells apoptosis within the tumor. Imatinib is therefore able to reduce the expression of 2,3-dioxygenase (Ido) of tumor cells. Ido enzyme is involved in the catayzation of immunosuppressive metabolites from tryptophan and therefore mediates downstream immunological response. Interestingly Imatininb resistant tumors, generally as a result of a second KIT mutation, restore the overexpression of IDO and combination of Imatinib with CTLA-4 blockade (a well established immunotherapeutic strategy) act synergistically. This insight provides some hints on something we have been suspecting for a long time. It is easy to predict consequences for rational design of combination therapies and strategies to overcome resistance in Imatinib resistant tumors.
8 Temmuz 2012 Pazar
Dental Did You Know: The Price of John Lennon's Tooth.
To contact us Click HERE
Apparently, John Lennon's molar was sold for about $31000 at the Omega Auction House on November 4th. It went for double its listed price and was originally given by him to his former housekeeper. It is also reported to be now in the possession of a Canadian dentist (not confirmed and not me :)
Source: Rolling Stone Magazine (Online), November 6th, Read November 7th, http://www.rollingstone.com/music/news/john-lennons-tooth-sells-for-more-than-31-000-at-auction-20111106
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Rolling Stone Magazine (Online), November 6th, Read November 7th, http://www.rollingstone.com/music/news/john-lennons-tooth-sells-for-more-than-31-000-at-auction-20111106
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Here we Grow Again: Now offering Invisalign Orthodontics!
To contact us Click HERE
One of the most heavily requested services in our practice has been orthodontics. Over the last year we've been steadily upgrading our skills in a variety of orthodontic techniques and are pleased to announce that we are officially adding Invisalign (no bracket) orthodontics to our practice. Invisalign allows for minor to moderate movement of teeth with clear aligners that are custom fit to each patient. Minor movements can be done in as little as 6-9 months, while more complex movements can usually be done in about 2 years.
Call Jodie at our front desk: (905) 273-7100 to book a consult appointment to further improve your smile and the health of your mouth.
Cheers!
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
One of the most heavily requested services in our practice has been orthodontics. Over the last year we've been steadily upgrading our skills in a variety of orthodontic techniques and are pleased to announce that we are officially adding Invisalign (no bracket) orthodontics to our practice. Invisalign allows for minor to moderate movement of teeth with clear aligners that are custom fit to each patient. Minor movements can be done in as little as 6-9 months, while more complex movements can usually be done in about 2 years.
Call Jodie at our front desk: (905) 273-7100 to book a consult appointment to further improve your smile and the health of your mouth.
Cheers!
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Happy New Year! Some Dental Resolutions for the New Year!
To contact us Click HERE
Happy New Year to everyone! May it be happy, healthy and prosperous!
Just wanted to give some dental resolutions that could be implemented with a little effort to ensure a great smile for the New Year:
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Just wanted to give some dental resolutions that could be implemented with a little effort to ensure a great smile for the New Year:
- Brush 2 minutes twice a day...yes, I said 2 minutes (not 1 minute or 30 seconds or once a day). It really does take that long to clean the majority of surfaces your mouth decently.
- Floss...yes, I know you tend to do it before dental appointments. However, 40% of your teeth are not being cleaned if you don't do it and a substantial percentage of cavities start in those areas
- Clean your tongue. I would say 95% of patients don't do this. A couple of quick swipes on the tongue is usually enough.
- Reduce your intake of candies/sweets: it will reduce the incidence of cavities, improve your blood sugar and weight.
- Drink more water. In moderation, this a great thing, especially after staining drinks like coffee, tea and wine. Want to reduce all that coffee/tea stain between hygiene appointments? Take a sip or two of water after you finish your drink.
- Regular maintenance appointments. Seeing your Doc/Hygienist for a checkup and scaling is truly the dental version of the oil change. Prevention is always the best option.
- Get things fixed while they are small (don't procrastinate). Dentistry seemingly operates on an exponential cost scale as things get more involved and complex. Getting a restoration that costs a couple of hundred dollars (and is usually covered by insurance) is much better for you and your pocketbook than letting it turn into a multi-thousand dollar root canal/core/crown or implant
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
To contact us Click HERE
Saw this infographic from Carrington College's Dental Assisting Program in California. I'm not sure I agree with the personality aspects of this graphic, but it's interesting to note what is out there in terms of information.
Source: http://carrington.edu/cccblog/programs/dental-assisting/teeth-and-your-personality/
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: http://carrington.edu/cccblog/programs/dental-assisting/teeth-and-your-personality/
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Let's immune system help
To contact us Click HERE
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido,
Vinod P Balachandran, et al. Nature Medicine17 (2011)
I would like to hilight this paper to our readership, as many of your are involved in the design of clinical trials and selection of potential biomarkers. This report is one of a handful of high impact papers that report the coperative role that inflammatory infiltrate and non cell autonomous effectors play in modulating response to established agents. This study demonstrates an interesting immunological mechanism of Imatininb that contributes to the antitumor effect in a Gastrointestinal Stromal Tumor (GIST) mouse model. Inflammatory infiltrate is a known finding in GIST specimens (including intratumoral CD8+ Tcells, Treg cells and macrophages). Acording to the authors, Imatinib activates CD8+ T cells and induces Treg cells apoptosis within the tumor. Imatinib is therefore able to reduce the expression of 2,3-dioxygenase (Ido) of tumor cells. Ido enzyme is involved in the catayzation of immunosuppressive metabolites from tryptophan and therefore mediates downstream immunological response. Interestingly Imatininb resistant tumors, generally as a result of a second KIT mutation, restore the overexpression of IDO and combination of Imatinib with CTLA-4 blockade (a well established immunotherapeutic strategy) act synergistically. This insight provides some hints on something we have been suspecting for a long time. It is easy to predict consequences for rational design of combination therapies and strategies to overcome resistance in Imatinib resistant tumors.TweetShare
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido,
Vinod P Balachandran, et al. Nature Medicine17 (2011)
I would like to hilight this paper to our readership, as many of your are involved in the design of clinical trials and selection of potential biomarkers. This report is one of a handful of high impact papers that report the coperative role that inflammatory infiltrate and non cell autonomous effectors play in modulating response to established agents. This study demonstrates an interesting immunological mechanism of Imatininb that contributes to the antitumor effect in a Gastrointestinal Stromal Tumor (GIST) mouse model. Inflammatory infiltrate is a known finding in GIST specimens (including intratumoral CD8+ Tcells, Treg cells and macrophages). Acording to the authors, Imatinib activates CD8+ T cells and induces Treg cells apoptosis within the tumor. Imatinib is therefore able to reduce the expression of 2,3-dioxygenase (Ido) of tumor cells. Ido enzyme is involved in the catayzation of immunosuppressive metabolites from tryptophan and therefore mediates downstream immunological response. Interestingly Imatininb resistant tumors, generally as a result of a second KIT mutation, restore the overexpression of IDO and combination of Imatinib with CTLA-4 blockade (a well established immunotherapeutic strategy) act synergistically. This insight provides some hints on something we have been suspecting for a long time. It is easy to predict consequences for rational design of combination therapies and strategies to overcome resistance in Imatinib resistant tumors.TweetShare
7 Temmuz 2012 Cumartesi
The nutrition of feral cats
To contact us Click HERE
Plantinga EA, Bosch G, Hendriks WH. Estimation of the dietary nutrient profile of free-roaming feral cats: possible implications for nutrition of domestic cats. Br J Nutr 2011;106 Suppl 1:S35-48.
Cats in the wild rely solely on animal tissues to meet their specific and unique nutritional requirements. This has led to unique digestive and metabolic adaptations. In order to better understand how the domestic cat has adapted to its physiologic needs, the diet of feral cats was assessed. The researchers reviewed 27 published studies reporting the feeding habits of feral cats and obtained data on the nutrient composition of the cats’ prey. The results showed that feral cats are obligatory carnivores with a diet high in protein (52% of daily energy) and fat (46% of daily energy) content, but low in carbohydrates (2% of daily energy). Minerals and trace elements appeared to be consumed in higher concentrations than current recommended allowances. The authors conclude that future research should focus on the value of feeding a natural diet of whole prey as an enhancement of feline health and longevity. [MK]
Related articles: Zaghini G, Biagi G. Nutritional peculiarities and diet palatability in the cat. Vet Res Commun 2005;29 Suppl 2:39-44.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Cats in the wild rely solely on animal tissues to meet their specific and unique nutritional requirements. This has led to unique digestive and metabolic adaptations. In order to better understand how the domestic cat has adapted to its physiologic needs, the diet of feral cats was assessed. The researchers reviewed 27 published studies reporting the feeding habits of feral cats and obtained data on the nutrient composition of the cats’ prey. The results showed that feral cats are obligatory carnivores with a diet high in protein (52% of daily energy) and fat (46% of daily energy) content, but low in carbohydrates (2% of daily energy). Minerals and trace elements appeared to be consumed in higher concentrations than current recommended allowances. The authors conclude that future research should focus on the value of feeding a natural diet of whole prey as an enhancement of feline health and longevity. [MK]
Related articles: Zaghini G, Biagi G. Nutritional peculiarities and diet palatability in the cat. Vet Res Commun 2005;29 Suppl 2:39-44.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Heart disease in Siberian cats
To contact us Click HERE
Progress report, Winn grant MT08-001
SNP analysis in Siberian cats with hypertrophic cardiomyopathy
Investigator: Robert A. Grahn, University of California-Davis
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disorder of domestic cats. The disease has been identified in many breeds, such as the Maine Coon, Ragdoll, American Shorthair, Devon Rex, Sphynx, Bengal, and Siberian. Mutations in the gene MYBPC3 have been found in Ragdolls and Maine Coons with HCM, but this mutation is not known to be responsible for HCM in other breeds to date. Feline HCM closely resembles human HCM which results from mutations in any of 7 candidate genes. Over 100 samples from Siberian cats have been submitted to the investigator’s lab for HCM testing. So far, a number of candidate genes have been eliminated as the cause of HCM in this breed. One chromosomal region has been identified that has likelihood of linkage to the disease. In humans, this genomic region is associated with cardiovascular disease, so it appears to be a likely candidate for HCM in the Siberian cat and research is ongoing. [MK]
See also: Meurs KM, Norgard MM, Kuan M, et al. Analysis of 8 sarcomeric candidate genes for feline hypertrophic cardiomyopathy mutations in cats with hypertrophic cardiomyopathy. J Vet Intern Med 2009;23:840-843.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
SNP analysis in Siberian cats with hypertrophic cardiomyopathy
Investigator: Robert A. Grahn, University of California-Davis
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disorder of domestic cats. The disease has been identified in many breeds, such as the Maine Coon, Ragdoll, American Shorthair, Devon Rex, Sphynx, Bengal, and Siberian. Mutations in the gene MYBPC3 have been found in Ragdolls and Maine Coons with HCM, but this mutation is not known to be responsible for HCM in other breeds to date. Feline HCM closely resembles human HCM which results from mutations in any of 7 candidate genes. Over 100 samples from Siberian cats have been submitted to the investigator’s lab for HCM testing. So far, a number of candidate genes have been eliminated as the cause of HCM in this breed. One chromosomal region has been identified that has likelihood of linkage to the disease. In humans, this genomic region is associated with cardiovascular disease, so it appears to be a likely candidate for HCM in the Siberian cat and research is ongoing. [MK]
See also: Meurs KM, Norgard MM, Kuan M, et al. Analysis of 8 sarcomeric candidate genes for feline hypertrophic cardiomyopathy mutations in cats with hypertrophic cardiomyopathy. J Vet Intern Med 2009;23:840-843.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Risk factors for FIP in Australian cats
To contact us Click HERE
Worthing KA, Wigney DI, Dhand NK, et al. Risk factors for feline infectious peritonitis in Australian cats. J Feline Med Surg 2012;14:405-412.
The purpose of this study was to determine whether patient signalment (age, breed, sex, and neuter status) is associated with naturally-occurring feline infectious peritonitis (FIP) in cats in Australia. FIP is a feline coronavirus-induced disease. There have been several risk factors discussed in association with the development of FIP. The disease is more frequent in cats less than 2 years of age, cats that reside in multi-cat environments, and in pedigreed cats. Early studies suggested FIP has a bimodal age distribution, though recent studies do not support this observation. In this study, the patient signalment of 382 confirmed cases of FIP were compared with a general cat population. Younger cats were significantly over-represented among FIP cases and a bi-modal age distribution was not found. Pedigreed cats were significantly over-represented and domestic crossbreeds under-represented in FIP cases. Several breeds were over-represented, including British Shorthair, Devon Rex, and Abyssinian. Male cats had a significantly higher proportion of representation than female cats. Domestic crossbred, Persian, and Himalayan cats were significantly under-represented in the FIP cohort of this study. [VT]
See also: Pesteanu-Somogyi L, Radzai C, Pressler B. Prevalence of feline infectious peritonitis in specific cat breeds. J Feline Med Surg 2006;8:1-5.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
The purpose of this study was to determine whether patient signalment (age, breed, sex, and neuter status) is associated with naturally-occurring feline infectious peritonitis (FIP) in cats in Australia. FIP is a feline coronavirus-induced disease. There have been several risk factors discussed in association with the development of FIP. The disease is more frequent in cats less than 2 years of age, cats that reside in multi-cat environments, and in pedigreed cats. Early studies suggested FIP has a bimodal age distribution, though recent studies do not support this observation. In this study, the patient signalment of 382 confirmed cases of FIP were compared with a general cat population. Younger cats were significantly over-represented among FIP cases and a bi-modal age distribution was not found. Pedigreed cats were significantly over-represented and domestic crossbreeds under-represented in FIP cases. Several breeds were over-represented, including British Shorthair, Devon Rex, and Abyssinian. Male cats had a significantly higher proportion of representation than female cats. Domestic crossbred, Persian, and Himalayan cats were significantly under-represented in the FIP cohort of this study. [VT]
See also: Pesteanu-Somogyi L, Radzai C, Pressler B. Prevalence of feline infectious peritonitis in specific cat breeds. J Feline Med Surg 2006;8:1-5.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Winn’s annual symposium on feline health
To contact us Click HERE
Winn’s 34th annual symposium on feline health was held on June 28, 2012 in Quincy, MA with an audience of over 100 cat owners and veterinarians. Dr. Leslie Lyons of the University of California, Davis presented an update on recent advances in genetic research and newly discovered mutations causing disease in cats. For example, recently the mutation causing a craniofacial defect in Burmese kittens was confirmed in Dr. Lyons’ laboratory. Winn has helped support Dr. Lyons’ research to improve cat health for many years.
Dr. John Rush of Tufts University discussed hypertrophic cardiomyopathy (HCM), covering disease presentation, diagnosis, and treatment. HCM is the most common cardiac disease in cats and causes the death of many cats every year. Winn’s Ricky Fund was established to further research into this important disease and has funded many projects to date, including discovery of genetic mutations associated with HCM in certain cat breeds. This year, Winn funded three new feline health project at Tufts University.
Another important event at the Symposium was the presentation of Winn’s 2012 Media Appreciation Award to Darlene Arden for her dedication to feline health and welfare. Read more about the award on Winn’s website.
More photos from the Symposium can be found on Winn board member Steve Dale’s blog.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
 |
| Dr. Leslie Lyons, Dr. John Rush, Steve Dale (L to R) |
 |
| Award winner Darlene Arden |
More photos from the Symposium can be found on Winn board member Steve Dale’s blog.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
Treatment of cats with FeLV or FIV
To contact us Click HERE
Doménech A, Miró G, Collado VM et al: Use of recombinant interferon omega in feline retrovirosis: From theory to practice, Vet Immunol Immunopathol 143:301, 2011.
The feline retrovirus infections – feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) - cause lifelong infections often with chronic disease. To date, treatment has been primarily symptomatic and supportive. These investigators examined the usefulness of interferon as a more specific treatment. Interferon is a protein in the blood that can modify the immune response and that has antiviral capabilities. Interferon-omega is a type of interferon found in cats that has been cloned and synthesized and is commercially available in some countries. Clinical improvement was observed when interferon-omega was used to treat 11 cats with FeLV or FIV. Certain blood parameters, such as amount of red blood cells, also improved. While no antiviral effects were seen, the improved clinical condition of the infected cats support the use of interferon-omega in treating retrovirus-infected cats. [MK]
See also: de Mari K, Maynard L, Sanquer A et al: Therapeutic effects of recombinant feline interferon-omega on feline leukemia virus (FeLV)-infected and FeLV/feline immunodeficiency virus (FIV)-coinfected symptomatic cats, J Vet Intern Med 18:477, 2004.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
The feline retrovirus infections – feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) - cause lifelong infections often with chronic disease. To date, treatment has been primarily symptomatic and supportive. These investigators examined the usefulness of interferon as a more specific treatment. Interferon is a protein in the blood that can modify the immune response and that has antiviral capabilities. Interferon-omega is a type of interferon found in cats that has been cloned and synthesized and is commercially available in some countries. Clinical improvement was observed when interferon-omega was used to treat 11 cats with FeLV or FIV. Certain blood parameters, such as amount of red blood cells, also improved. While no antiviral effects were seen, the improved clinical condition of the infected cats support the use of interferon-omega in treating retrovirus-infected cats. [MK]
See also: de Mari K, Maynard L, Sanquer A et al: Therapeutic effects of recombinant feline interferon-omega on feline leukemia virus (FeLV)-infected and FeLV/feline immunodeficiency virus (FIV)-coinfected symptomatic cats, J Vet Intern Med 18:477, 2004.
More on cat health:
Winn Feline Foundation Library
Find us on Facebook
Follow us on Twitter
Read the Cat Health News Weekly
Join us on Google+
5 Temmuz 2012 Perşembe
Dental Did You Know: Warfarin
To contact us Click HERE
Warfarin, a vitamin K antagonist has been an effective oral anti-coagulant for over 50 years. It was discovered in 1945 as a result of research at the University of Wisconsin looking into a pesticide for mice and rats. (Patients may need additional management involving certain dental procedures such as extractions)
Source: Feferman I, Healthline: End of an Era (Warfarin), Ontario Dentist, Dec 2011, Vol 88, No 10, pg 16-17.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Feferman I, Healthline: End of an Era (Warfarin), Ontario Dentist, Dec 2011, Vol 88, No 10, pg 16-17.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Dental Did You Know: The Increasing Rate of Caries (Cavities) in Children
To contact us Click HERE
The prevalence of dental decay in the United States (and presumably in Canada) in children aged 2-5 has increased 15.2% according to recent data from the Center for Disease Control and Prevention. Factors that influence this rate include:
Source: Cohn C, Why Does My Child Get So Many Cavities? What Can I Do About It?, Oral Health, January 2012, Vol 102, No 1, pg 46-53.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
- Active dental caries in the primary caregiver
- Socioeconomic status
- Dental IQ
- Medical history
- Dietary habits
Source: Cohn C, Why Does My Child Get So Many Cavities? What Can I Do About It?, Oral Health, January 2012, Vol 102, No 1, pg 46-53.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Dental Did You Know: Smoking Rates for Canadians
To contact us Click HERE
Health Canada's Canadian Tobacco Use Monitoring Survey in 2010 reported that 17% of the population older than 15 years smoked. The rate among youth aged 15-19 was 12%.
Source: Dean B, Oral Health Month-Start a Conversation, Save a Life, Ontario Dentist, Jan/Feb 2012, Vol 89, No 1, pg 52-53.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Dean B, Oral Health Month-Start a Conversation, Save a Life, Ontario Dentist, Jan/Feb 2012, Vol 89, No 1, pg 52-53.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Dental Did You Know: Sports Drinks, Acidity and the Effects on Teeth
To contact us Click HERE
Most sports drinks are quite acidic (pH 3-4) and if taken to excess, may lead to dental erosion and demineralization. One study found that 57% of 11-14 year-olds had evidence of some dental erosion.
Source: Feferman I, Healthline: Risks of Sports Drinks, Ontario Dentist, March 2012, Vol 89, No 2, pg 20-21.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Feferman I, Healthline: Risks of Sports Drinks, Ontario Dentist, March 2012, Vol 89, No 2, pg 20-21.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Dental Did You Know: White Spot Lesions After Orthodontic Treatment
To contact us Click HERE
95% of patients develop at least one white spot lesion or enamel surface decalcification following orthodontic treatment. Oral hygiene discussions before treatment helped reduce the incidence of these lesions.
Source: Sevels I, Clinical Abstracts: White Spot Lesions After Orthodontic Treatment, Oral Health, June 2012, Vol 89, No 5, pg 16-17.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Source: Sevels I, Clinical Abstracts: White Spot Lesions After Orthodontic Treatment, Oral Health, June 2012, Vol 89, No 5, pg 16-17.
Hans Skariah, B.Sc., DMD
Promenade Court Dental Health Group in Mississauga
2233 Hurontario St., Mississauga, ON, Canada
(1/2 km north of the QEW in the Dome Building)
(905) 273-7100
Kaydol:
Yorumlar (Atom)